Motoric cognitive risk syndrome and mortality: Results from the EPIDOS cohort


Cognitive impairment, slow walking speed and Motoric Cognitive Risk syndrome (MCR) have separately been associated with an increased risk for mortality in the short term.


  • To examine the relationship between MCR and its components (i.e., Subjective Cognitive Complaint—SCC—and slow walking speed) with short, medium and long terms mortality rates in community-dwelling elders


The design is a prospective observational cohort study.

3,778 participants were selected from the EPIDémiologie de l’OStéoporose (EPIDOS) study. MCR was defined as the combination of slow walking speed and SCC in participants not suffering from major neurocognitive disorders. Deaths were prospectively recorded with the help of mail-in and phone surveys, and of the French national death registry at 5, 10, 15 and 19 (end of follow-up period) years.


Slow walking speed and MCR were associated with an increased risk in mortality in the medium and long terms. No associations, however, were found with SCC.


Jewish General Hospital, Montreal

Faculty of Medicine, McGill University

Canada Gait Consortium